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Clinical Research Trials Available

The following Clinical Research Trials are available through Mercy.   Additional information can be found at


Infectious Disease 419-251-4919

Clostridium difficille infection (C-Diff) Protocol link
  A multi-center, randomized, double-blind study to compare the efficacy and safety of cadazolid versus vancomycin in subjects with Clostridium difficile associated diarrhea
Sepsis Protocol link
  A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Assess the Safety and Efficacy of ART-123 in Subjects with Severe Sepsis and Coagulopathy
Bacterial Skin Infections Protocol link
  A Phase 3b, Double-Blind, Multicenter, Randomized Study to Compare the Efficacy and Safety of single Dose Dalbavancin to a Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections
  A Phase 3, multicenter, randomized, double-blind, active-controlled study to evaluate the efficacy and safety of IV and oral delafloxacin compared with vancomycin + aztreonam in patients with acute bacterial skin and skin structure infections.  

PULMONARY 419-251-4919

COPD Protocol link
  A Double-blind, Randomized, Placebo-controlled, Parallel-group, Phase IV study to evaluate the effect of Aclidinium Bromide on long-term Cardiovascular safety and COPD exacerbations in Patients With Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD). Phase 4-Tudorza
  A randomized, double-blind, active-controlled parallel group study to evaluate the effect of 52 weeks of once daily treatment of orally inhaled tiotropium + olodaterol fixed dose combination compared with tiotropium on Chronic Obstructive Pulmonary Disease (COPD) exacerbation in patients with severe to very severe COPD. [DYNAGITO I]  

SLEEP 419-251-4919

Narcolepsy Protocol link
Pediatric A Randomized, Open-Label Study to Characterize the Pharmacokinetics, Pharmacodynamics, and Safety of Single and Multiple Doses of armodafinil (50, 100 and 150 mg per day) in Children and Adolescents with Excessive Sleepiness Associated with Narcolepsy

CARDIAC 419-251-4919

Atrial Fibrilation Protocol link
  GLORIA - AF: Global Registry on Long-Term Oral Anti-thrombotic TReatment In PAtients with Atrial Fibrillation (Phase II/III) 
Cardiac Intervention Protocol link
Leads Product Surveillance Registry
STENT BIOTRONIK - A Prospective Randomized Multicenter Study to Assess the Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in the Treatment Og Subjects With up to Three De Novo or Restenotic Coronary Artery Lesions - V  
Randomized Controlled Trial Clinical Evaluation of the ABSORB™ Bioresorbable Vascular Scaffold (BVS) in the Treatment of Subjects with de novo Native Coronary Artery Lesions

Oncology 419-251-4919

Lung Protocol link
Non-Squamous, non-small cell A Phase III open label randomized study of MPDL3280A (Anti-PD-L1 Antibody) in combination with carboplatin + paclitaxel with or without bevacizumab compared with carboplatin + paclitaxel + bevacizumab in chemotherapy naïve patients with stage IV non squamous non-small cell lung cancer
Hematology Protocol link
Multiple Myeloma A Phase 3, Randomized, Double-Blind, Multicenter Study Comparing Oral MLN9708 Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Patients With Newly Diagnosed Multiple Myeloma
Advanced B-Cell An open label,Phase 1/2 study of MEDI-551, A Humanized Monoclonal Antibody Directed against CD19, in adult subjects with relapsed or refractory advanced B-cell Malignancies
Pancreatic Protocol link
Advanced or metastatic Adenocarcinoma of the Pancreas A randomized,double blind phase 3 study of the JAK1/2 inhibitor, ruxolitinib or placebo in combination with Capecitabine in subjects with advanced or metastatic adenocarinoma of the pancreas who have failed or are intolerant to first line chemotherapy 
Other Protocol link
Polycythemia Vera Prospective non intervential study of disease progression and treatment of patients with polycythemia vera in United States academic or community clinical practices  (REVEAL)
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