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Síndrome de Gilbert

Definición

Es un trastorno común transmitido de padres a hijos. Dicho trastorno afecta la forma como la bilirrubina es procesada por el hígado y causa ictericia.

Nombres alternativos

Ictericia juvenil intermitente; Hiperbilirrubinemia crónica leve; Ictericia familiar no hemolítica - no obstructiva; Disfunción hepática constitucional; Bilirrubinemia benigna no conjugada

Causas

La enfermedad de Gilbert afecta hasta el 10% de las personas en algunas poblaciones de raza blanca y es una afección que generalmente no es cancerosa ( benigna).

Síntomas

  • Fatiga
  • Coloración amarillenta de la piel y la esclerótica de los ojos (ictericia leve)

Nota: la ictericia aparece clásicamente durante momentos de esfuerzo, estrés, falta de alimento e infección.

Pruebas y exámenes

Un examen de bilirrubina indirecta en sangre muestra cambios que ocurren con la enfermedad de Gilbert.

Tratamiento

No se necesita ningún tratamiento para la enfermedad de Gilbert.

Grupos de apoyo

Pronóstico

La ictericia puede aparecer y desaparecer a lo largo de su vida, especialmente durante padecimientos como los resfriados. Sin embargo, generalmente no causa problemas de salud.

Posibles complicaciones

No existen complicaciones conocidas.

Cuándo contactar a un profesional médico

Consulte con el médico si presenta ictericia o dolor abdominal persistente.

Prevención

No hay una forma de prevención comprobada.

Referencias

Berk PD, Korenblat KM. Approach to the patient with jaundice or abnormal liver test results. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 150.

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    Review Date: 4/23/2009

    Review By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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