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Persantine/Rest Stress Cardiac Imaging Banner

Persantine/Rest Stress Cardiac Imaging

What is the doctor looking for?

Decreased blood flow to the heart muscle and/or heart muscle damage.


What is the test?

This is a 2-part test. One part involves taking pictures of the heart at rest one hour after an injection of a radionuclide (This is NOT a dye!) The other set of pictures will be taken of the heart at stress 1 hour after persantine and the radionuclide is injected through an IV during stress test. Persantine is given to show what a heart looks like at stress when a patient is not physically able to increase their heart rate on a treadmill. These tests may be done in one day or separate days according to the schedule.


Where are the tests done?

In the heart station stress lab and in nuclear medicine.


May I eat or drink?

Not for 6 hours prior to the test. You may have a sip of water with medications, unless otherwise directed by your physician. For 24 hours prior to your test do NOT have:

  • Caffeinated or Decaffeinated soft drinks
  • Caffeinated or Decaffeinated coffee or tea
  • Any foods containing chocolate
  • Avoid pepper
  • Energy drinks

What about medications?

You need to discuss your medications with your doctor or nurse. You should be off Theophylline medications for 24 hours before the test. If you are diabetic, take half of your usual insulin. You may bring the rest of your dose and something to eat or drink if you feel you will need it. Do NOT take the pill form of diabetes medication unless otherwise instructed. All other medications except those we mentioned may be taken with a sip of water. If you have any questions, please call your doctor.


Will I have an IV?



Do I need special clothing?

Wear comfortable shoes and clothing.


What should I bring to the test?

You may want to bring something to read to help pass the time.


How long does the test take?

Approximately 2 hours for the resting part of the test and 2 hours for the stress part of the test.


When will the results be ready?

Results are generally available to your physician within 24 hours.


Tell your doctor/nurse if you have …

Asthma, COPD, breathing problems, or if you have any chest pain.


Will the test make me sick or sleepy?

It may cause flushing, or a headache. It will not make you sleepy.


Will I receive any radiation during the procedure?

A small amount of radiation is received. Increasing your intake of fluids will help remove the radiation through the urine.


What if I am pregnant or breast-feeding?

Notify your physician, as this test may not be appropriate.

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