Obesity Linked to Aggressive Prostate Cancer
Two recent studies have found that obese men who had had radical prostatectomy to treat their prostate cancer (surgery to remove the prostate) were more likely to have aggressive cancers and they were more likely to have their cancers return after the surgery. In both studies, the obese men who were participating were more likely to be African American. Researchers have long wondered why African American men with prostate cancer are more likely to die from the disease and more likely to have aggressive cancers.
Researchers believe that hormones and proteins that are found in higher quantities in obese men may contribute to faster tumor growth.
The studies also showed that obese prostate cancer patients who brought their weight to a more normal range decreased their chances of a recurrence of their cancers. And obese men who have not had cancer may be able to decrease their risk of developing prostate cancer if they can get their weight into a healthier range.
Journal of Clinical Oncology, 22 December 2003.